Phenytoin bone loss

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August undefined, 2024

WebApr 29, 2008 · Significant loss (2.6%) was seen at the femoral neck in the phenytoin group. BMD remained stable in the other AED groups. Bone turnover markers and calciotropic hormones were unchanged after 1 year in all groups except for a significant decline in urine N-telopeptide in the phenytoin group. WebMar 15, 2024 · a diet lacking calcium and vitamin D. smoking or using other forms of tobacco. drinking too much alcohol or caffeine. taking prednisone or phenytoin. Certain other conditions can also increase ...

Phenytoin Oral: Uses, Side Effects, Interactions, Pictures ... - WebMD

WebApr 28, 2008 · Treatment with the anti-seizure medication phenytoin appears to lead to the loss of bone mineral density at the hip in young women, whereas treatment with other antiepileptic agents, such as ... WebJul 11, 2024 · National Center for Biotechnology Information auton ostaminen yksityiseltä

Side Effects of Dilantin (phenytoin) - MedicineNet

WebApr 3, 2024 · These medications can help prevent bone loss caused by anti-androgen medications. 6. Certain seizure medications. Carbamazepine (Tegretol), phenytoin (Dilantin), and divalproex (Depakote) are taken to prevent … WebPhenytoin may cause swelling and bleeding of the gums. Massage your gums and brush and floss your teeth regularly to minimize this problem. See your dentist regularly. WebIt is also evident that repeated administration of phenytoin may cause osteopenia which may be due to bone loss by inhibiting bone formation and/or by accelerating bone resorption rather than osteoid accumulation. The bone loss is not rachitic because of the lack of increase in osteoid thickness. gb55002

Antiseizure Drugs and Reduced Bone Density Neurology

Osteoporosis Endocrine Society

WebOsteoporosis is caused by a loss of bone mineral density (BMD). This happens to most of us as we get older. It also affects women more than men, for example after the menopause. Researchers are still trying to find out exactly how epilepsy medicines cause bones to lose strength and BMD. WebAdministration of phenytoin significantly decreased bone strength and BMD, which was associated with enhanced bone resorption. In contrast, treatment with gabapentin (150 … auton ostaminen saksastaWebFeb 9, 2024 · Phenytoin may cause liver problems. Check with your doctor right away if you have pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, vomiting, or yellow eyes or skin. Phenytoin can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. auton ostaminen ruotsista

"WebDec 11, 2014 · the available data suggests that phenytoin, carbamazepine, primidone, and sodium valproate are associated with decreased bone mineral density, which may lead to … " - Phenytoin bone loss

Phenytoin bone loss

WebJun 8, 2004 · The rate of bone loss was almost two times greater per year for those who took phenytoin. This increased rate of bone density loss has the potential to increase the … WebDilantin might not be the only antiepileptic medication causing bone loss. Discussed your situation with your neurologist, or physician, to see if they have any recommendations or …

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WebApr 14, 2024 · Phenytoin oral capsule is used to treat tonic-clonic and complex partial seizures in people with epilepsy. It’s available as a generic drug and as the brand-name … WebAs far as contraindications go, phenytoin should be avoided during pregnancy, as well as in clients with sinus bradycardia, heart block, and Adams-Stokes syndrome, which refers to a condition characterized by syncopal episodes caused by cardiac arrhythmias.

WebPhenytoin overdose has been described (101 A).. A 32-year-old man developed ataxia and nystagmus 1 hour after taking about 175 tablets of phenytoin 100 mg.He was given oral … WebNational Center for Biotechnology Information

WebTacrolimus, a calcineurin inhibitor, affects bone metabolism and increases the risk of fracture due to marked bone loss. Bisphosphonates increase the bone mineral density (BMD) in osteoporosis patients. Menatetrenone has less positive effects on BMD but reduces the risk of fracture by improving bone quality. WebFeb 1, 2009 · Macrocytosis can occur when there is increased RBC production secondary to peripheral blood cell destruction (i.e., hemolysis) or loss (i.e., hemorrhage), leading to a reticulocytosis....

WebThis literature review confirms that long-term use of phenytoin causes gingival hyperplasia, as does the use of valproate, carbamazepine and phenobarbital. Patients taking carbamazepine or phenytoin had alveolar bone loss. However, the effects of newer-generation antiepileptic drugs on oral health have not yet been studied.

WebDec 22, 2006 · Certain anticonvulsants may cause bone loss. 7 The medications most commonly associated with osteoporosis include phenytoin, phenobarbital, … gb5491WebJul 30, 2024 · This condition happens when your body gets rid of more bone than it is creating. ... Horizant, Neurontin), or phenytoin (Dilantin ... 8 Exercises to Boost Bone Health . Reduce bone loss and build ... auton osto italiastaWebJan 24, 2024 · Certain medications can cause bone loss if used for a longer time. Use over a short time, such as a few weeks, is usually not a problem. Broken bones can lead to pain and disability. For example, some older … gb55008WebThe topical application of DPH may be a therapeutic treatment to prevent bone loss induced by local inflammation such as periodontitis. ... To test the direct actions of phenytoin on human bone cells, we measured the dose responses to phenytoin for [3H]thymidine incorporation, cell number, alkaline phosphatase specific activity, and collagen ... gb55009WebApr 14, 2024 · low levels of calcium and phosphate softening of your bones (can lead to broken bones, osteopenia, or osteoporosis) Severe confusion. If your blood levels of phenytoin are above the recommended... gb55023WebFeb 25, 2024 · Mouse Study Points to Strategy for Preserving Bone During Chemotherapy. In this image of a normal mouse bone, the red and green lines represent new bone. Exposure to chemotherapy and radiation leads to bone loss and increases the risk of osteoporosis and fractures. A new study in mice suggests that a biological process known as cellular ... auton osto ilman luottotietojaWebMar 21, 2024 · Initial dose (phenytoin-naive): 100 mg orally 3 times a day; tablets can be chewed thoroughly before swallowing or swallowed whole. Adjust dose as needed; most adults can be maintained on 300 to 400 mg/day in divided doses. Maximum dose: 600 mg/day. ORAL ADMINISTRATION: Oral Suspension: Initial dose (phenytoin-naive): 125 mg … auton osto espanjassa