Mouse hepatic stellate cell line
Nettet23. jul. 2015 · Intrahepatic implantation of mouse HCC cell lines requires 30 min per mouse. ... In addition, staining for the hepatic stellate cell activation markers α-SMA, ... Nettet23. nov. 2024 · Fate-Mapping Evidence That Hepatic Stellate Cells Are Epithelial Progenitors in Adult Mouse Livers. Stem Cells. 26, 2104–2113 (2008). Article CAS PubMed PubMed Central Google Scholar DeLeve, L ...
Mouse hepatic stellate cell line
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Nettet10. mai 2024 · Activation of hepatic stellate cells (HSCs) in liver injury is the primary driver of hepatic fibrosis. In this Review, Tsuchida and Friedman detail the varied … Nettet1. nov. 2024 · The hepatic stellate cells (HSCs) localize at the space of Disse in the liver and have multiple functions. They are identified as the major contributor to hepatic fibrosis. Significant understanding of HSCs has been achieved using rodent models and isolated murine HSCs; as well as investigating human liver tissues and human HSCs. There is …
Nettet31. des. 2024 · Hepatic stellate cells in the normal human liver express both cellular retinol-binding protein-1 (CRBP-1) and αSM-actin, while myofibroblasts express only αSM-actin in fibrotic or cirrhotic liver, suggesting a change of stellate cells to myofibroblasts due to chronic inflammation [ 30 ]. NettetIn this study, we used the human hepatic stellate cell line LX-2 and the classical CCl4-induced hepatic fibrosis mouse model for in vitro and vivo experiments. We found that …
NettetDamage in Mice Juan E. Puche,1,2 Youngmin A. Lee,1 Jingjing Jiao,1 Costica Aloman,1 Maria I. Fiel,1 Ursula Mu~noz, 1,2 Thomas Kraus,4 Tingfang Lee,1 Hal F. Yee, Jr.,3 … Nettet11. apr. 2024 · During chronic hepatitis B virus (HBV) infection, hepatic fibrosis is a serious pathological condition caused by virus-induced liver damage. The activation of …
Nettet12. apr. 2024 · Experiments were performed in wild-type and FNDC5 −/− mice, primary mouse HSCs, and human hepatic stellate cell line (LX2). Mice were treated with carbon tetrachloride (CCl 4) or bile duct ligation (BDL) to induce liver fibrosis. EVs derived from HSCs were purified and injected intraperitoneally into mice.
NettetMouse Hepatic Stellate Cells (MHSteC) provided by Innoprot are isolated from swiss mouse liver tissue. MHSteC are cryopreserved immedaitelly after isolation and delivered frozen. Each vial of Mouse Hepatic … thundermist mental healthNettetMethods: Experiments were performed in wild-type and FNDC5-/-mice, primary mouse HSCs, and human hepatic stellate cell line (LX2). Mice were treated with carbon tetrachloride (CCl 4) or bile duct ligation (BDL) to induce liver fibrosis. EVs derived from HSCs were purified and injected intraperitoneally into mice. thundermist monoclonal antibody infusionNettetSCC064 Sigma-Aldrich LX-2 Human Hepatic Stellate Cell Line Download Zoom The LX-2 human hepatic stellate cell line has been extensively characterized and retain key features of hepatic stellate cytokine signaling, neuronal gene expression, retinoid metabolism, and fibrogen More>> thundermist medical woonsocket riNettet12. apr. 2024 · Experiments were performed in wild-type and FNDC5 −/− mice, primary mouse HSCs, and human hepatic stellate cell line (LX2). Mice were treated with … thundermist of woonsocket riNettetNormal mouse hepatocyte cell line FL83B (ATCC CRL-2390) was cultured in Ham’s F-12 K medium containing 10% fetal bovine serum ... liver fibrosis. Since HSCs are major sources of fibrogenic liver cells, it was expected that Daxx would be expressed in hepatic stellate cells; however, the IHC data indicated that Daxx was mainly expressed in ... thundermist of woonsocketNettetFor reasons that are not entirely known, males may be three to five times more likely than females to develop HCC, the most common type of liver cancer. 83% of cases are diagnosed in less-developed countries, with the highest rates found in east and southeast Asia and in middle and western Africa; rates are lower in south-central and western Asia. thundermist of south countyNettetActivated hepatic stellate cells are a major cellular source of MCP-1 in injured livers . In line with this, the expression of α-smooth muscle actin ( α-sma ), a marker for HSC activation, was upregulated in response to BDL, with significantly higher expression levels in the Fhl2 -deficient mice than the wt mice ( Figure 2 A). thundermist pcp