WebMar 8, 2013 · The synergistic effects of everolimus (RAD) and SN38 were assessed in CRC cell lines, HT29 (BRAF mt; PIK3CA mt; p53 mt), HCT116 (KRAS mt, PIK3CA mt), HCT8 (KRAS mt) and LS180 (KRAS mt; PIK3CA mt). For all in vitro experiments SN38 was used in place of irinotecan since SN38 is the active metabolite of irinotecan. WebAs shown in Figure 2A,B, compound 275# dramatically reduced the cell viability in HCT116 and HCT8 cell lines in a dose- and time-dependent manner. ... In addition, the protein level of p53 was not influenced by compound 275#, and we inferred that the proapoptotic effect of compound 275# may be not mediated by p53 (Figure S3, ...
HCT-8 [HRT-18] - CCL-244 ATCC
WebSep 8, 2024 · We also identified p53 as the target of circMYH9 and showed that circMYH9 can inhibit p53 by degrading p53 pre-mRNA with recruitment of the m 6 A reader hnRNPA2B1. p53 further transcriptionally represses PHGDH expression. Moreover, a ROS/HIF1α pathway that amplifies circMYH9 was identified under SG or Glu starvation. Web广西壮族自治区人民医院结直肠·肛门外科东院院区、结直肠·肛门外科北院院区开科. 为切实服务广大患者,推动「两院三区四门诊」建设,在院党委统一领导和部署下,经过大量前期筹备,4 月 10 日上午,广西壮族自治区人民医院 结直肠·肛门外科东院院区、结 ... dan technocraft plc
The silence of p66(Shc) in HCT8 cells inhibits the viability …
Webloss of contact with the substratum and neighboring cells. Biochemical studies using HCT8 and MCF7 cancer cells suggested that the cytotoxic effect of 1 and 2 might act via induction of mitochondrial mediated apoptosis. Data presented in this study warrants further investigation on the mode of action and underscores the importance of the WebInterestingly, LACTB could exert antitumorigenic effect only in HCT116 and HCT8 cells harboring wild-type TP53, but not in HT29 and SW480 cells harboring mutant TP53 or … Web"NS20Y Cells小鼠神经母细胞瘤贴壁细胞 GD-C0248632B66042 细胞背景资料:神经母细胞瘤;雄性;A/J 细胞物种来源:人源或鼠源等其它物种来源 细胞培养中支原体污染的经验分享:支原体是一类缺乏细胞壁的原核细胞型微生物,大小一般在0.3-0.5um之间,呈高度 birthday sayings for great granddaughter