WebCisplatin for injection is a highly emetogenic antineoplastic agent; premedicate with anti-emetic agents; without antiemetic therapy, marked nausea and vomiting occur in almost … WebAug 1, 2024 · For dosing modifications for cisplatin, carboplatin, or pembrolizumab, refer to their prescribing information. Preparation for Administration Alimta is a hazardous drug. Follow applicable special …
Cisplatin nephrotoxicity - UpToDate
WebMay 15, 2024 · Oncology Intravenous IV Dilution – Alphabetical Listing – Antineoplastic & Parenteral Agents. Link to new oncology drug entities – including oral and IV agents. WebCisplatin is a platinum-based agent whose nephrotoxicity is thought related to the chloride in the cis position. Cisplatin gains entry into tubular cells via uptake by the OCT-2 system on the basolateral membrane of proximal tubular cells. • Cellular apoptosis/necrosis develops due to endoplasmic reticulum-induced stress, mitochondrial injury pathways, … thundervpn下载
Oncology Intravenous IV Dilution - Parenteral Agents - GlobalRPH
WebSep 6, 2024 · Cisplatin injection is indicated as therapy to be employed as follows: Metastatic Testicular Tumors - In established combination therapy with other approved … WebFeb 1, 2024 · Cisplatin injection is used to treat advanced cancer of the bladder, ovaries, or testicles. Cisplatin is an antineoplastic agent (cancer medicine). It interferes with the … Webcisplatin 100 mg/m2 on Day 1 of a 21-day cycle or to etoposide 100 mg/m2 I.V. on Days 1, 2, and 3 and cisplatin 100 mg/m2 on Day 1 on a 21-day cycle (Table 3). There was no significant difference in survival between the two treatment arms (Logrank p=0.18, two-sided). The median survival was 8.7 months for the Gemzar plus cisplatin arm thunderwave 100w emergency police siren kit